New Injectables Offer More Comfortable Treatment With Lidocaine

Updated November 3, 2017
Published June 28, 2010 by

The FDA has recently granted approval for several wrinkle fillers that contain lidocaine for increased comfort.  These popular hyaluronic acid fillers can make your treatment experience easier, while providing the same results as previous versions.

3 injectable products were granted FDA approval in February 2010 for lidocaine versions in the U.S.:

  • Juvederm XC
  • Restylane-L
  • Perlane-L

Juvederm XC

In a clinical trial with the new Juvederm XC, 72 patients were blindfolded and injections were administered to the nasolabial folds – the lines that travel from the nose to the corners of your mouth.  Participants were treated with either Juvederm or Juvederm XC. Patients assessed pain levels during treatment and then 30 minutes and 24 hours post-treatment. In the study, 93 percent reported less pain when treated with the lidocaine formulation versus the non-lidocaine formulation of Juvederm.

Restylane L and Perlane L

Restylane and Perlane are now available in a more comfortable formula, with the addition of 0.3 percent lidocaine.   Just like the regular Restylane formula that has been available for years, Restylane – L is made with clear stabilized hyaluronic acid gel, a natural substance that already exists in your body tissue.

In clinical studies of the new formula, 71 percent of the 60 participants reported less pain after injection into the nasolabial fold than with Restylane alone.

Radiesse

The FDA also cleared a method for doctors mixing lidocaine with Radiesse in July 2009.

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